Blisters develop most often on the feet and are normally caused by a mixture of friction and pressure. They are very common and can be very painful. A blister is a fluid pocket in the skin which develops when the upper skin layers separate and the space between them fills with serum. Serum is the liquid part of the blood - it contains protective substances like antibodies. The appearance is of a bubble on the skin.
For people with diabetes , having too much glucose sugar in their blood for a long time can cause some serious complications, including foot and skin problems, as well as heart disease, stroke, kidney disease, eye damage, and other problems. If you have an infection that will not heal because of poor blood flow, you are at risk for developing gangrene, which is the death of tissue due to a lack of blood. To keep gangrene from spreading, the doctor may have to remove a toe, foot, or part of a leg. This procedure is called amputation. Diabetes is the most common, non-traumatic cause of leg amputations. Each year, more than 56, people with diabetes have amputations. However, research suggests that more than half of these amputations can be prevented through proper foot care.
DermNet provides Google Translate, a free machine translation service. Note that this may not provide an exact translation in all languages. A friction blister is a blister caused by the skin repeatedly rubbing against another object. It most often forms on the palms, fingers, soles, sides of the feet and toes. The top of the blister is rubbed off where skin is thinner, such as the top of the hand or foot, forming an abrasion.
Ulcers are typically defined by the appearance of the ulcer, the ulcer location, and the way the borders and surrounding skin of the ulcer look. Neuropathy and peripheral artery disease often occur together in people who have diabetes. Nerve damage neuropathy in the feet can result in a loss of foot sensation and changes in the sweat-producing glands, increasing the risk of being unaware of foot calluses or cracks, injury or risk of infection.